What does a positive varicella zoster virus IgG mean?

A positive IgG ELISA result indicates that a person has antibodies to VZV either from past varicella disease or vaccination. This test cannot distinguish whether the antibodies were from a past episode of varicella or vaccination.

What is varicella-zoster ABS IgG IgM?

A positive IgG result coupled with a negative IgM result indicates previous vaccination to or infection with VZV. These individuals are considered to have protective immunity to reinfection. A negative IgG result coupled with a negative IgM result indicates the absence of prior exposure to VZV and nonimmunity.

What does VZV IgM positive mean?

A positive IgM result indicates a recent infection with varicella-zoster virus (VZV). A negative result does not rule out the diagnosis of VZV infection. The specimen may have been drawn before the appearance of detectable antibodies.

What is the normal range for varicella zoster virus IgG?

0.8 AI or less: Negative – No significant level of detectable varicella- zoster IgG antibody. 0.9-1.0 AI: Equivocal – Repeat testing in 10-14 days may be helpful. 1.1 AI or greater: Positive – IgG antibody to varicella-zoster detected, which may indicate a current or past exposure/immunization to varicella-zoster.

What is the difference between varicella IgG and IgM?

When the body is infected with VZV, it defends itself by producing two types of antibodies in sequence: first, IgM, which appears 1 to 2 weeks after the infection and which is present for a few weeks before disappearing, then IgG, which appears a few weeks after IgM and which lasts for the rest of that person’s life.

What causes varicella-zoster virus?

Varicella (chickenpox) is an acute infectious disease. It is caused by varicella-zoster virus (VZV), which is a DNA virus that is a member of the herpesvirus group. After the primary infection, VZV stays in the body (in the sensory nerve ganglia) as a latent infection. Primary infection with VZV causes varicella.

What is the difference between varicella-zoster IgM and IgG?

How long does varicella IgM stay positive What does it mean if IgG is positive?

After VZV infection, IgG and IgM antibodies appear 2 to 5 days after the rash and show the highest titers at 2 to 3 weeks. The VZV IgM antibody levels then rapidly decrease and cannot be detected at 1 year after infection, and the IgG antibody levels gradually decrease, showing positive test results for several years.

How do you read varicella test results?

165.0 IV or greater: Positive – IgG antibody to varicella-zoster detected, which may indicate a current or past varicella-zoster infection. 0.90 ISR or less: Negative – No significant level of detectable varicella-zoster virus IgM antibody. 0.91-1.09 ISR: Equivocal – Repeat testing in 10-14 days may be helpful.

Is varicella zoster curable?

Shingles is caused by the varicella-zoster virus, the same virus that causes chickenpox. There are treatments for shingles symptoms, but there is no cure. There are vaccines against shingles and postherpetic neuralgia.

Where is varicella-zoster virus found?

Latent varicella–zoster virus is located predominantly in neurons in human trigeminal ganglia – PMC.